APVO news

Latest 7 stories · newest Nov 5, 2026

APVO
Aptevo reduces IRRs with mipletamig regimen

Aptevo successfully refined mipletamig's priming dose to reduce patient infusion reactions. This improves tolerability for frontline AML patients, strengthening the drug's profile for Phase 2 development.

APVO
Counsel Opinion Filed for Equity Offering

Aptevo Therapeutics filed an exhibit 5.1 legal opinion in relation to a sales agreement authorizing the sale of up to $2.3M in common stock, by Roth Capital Partners.

APVO
21% of AML patients went to stem cell transplant

Ten patients advanced to transplant after treatment with mipletamig, a 30-fold increase over historical VEN+AZA rates, supporting further clinical development.

APVO
Aptevo to Showcase Multispecific Platform at SITC 2026

Aptevo Therapeutics will present at the Society for Immunotherapy of Cancer to highlight its CD40-directed multispecific portfolio and platform technology designed to coordinate innate and adaptive immunity. This business update highlights the ce company's pipeline progress and remains relevant for …

APVO
Aptevo reports 93% clinical benefit rate with mipletamig triplet in TP53-mutated AML

Aptevo Therapeutics reported a 93% clinical benefit rate in evaluable TP53-mutated AML patients treated with its mipletamig triplet, nearly double published venetoclax outcomes, showcasing potential for a difficult-to-treat population.

APVO
Company files patent for Nectin-4 x PD-L1 dual-targeting backbone

Aptevo Therapeutics filed a patent application covering a versatile Nectin-4 x PD-L1 backbone intended to support multiple solid tumor therapies and unlock value for partners.

APVO
Aptevo and Niowave launch 50/50 radiopharmaceutical collaboration with 7.9% equity stake

Aptevo Therapeutics and Niowave announced a strategic partnership to develop up to three radiopharmaceutical oncology programs, with Niowave making an at-the-market equity investment representing 7.9% ownership and potential to reach 19.99% through warrants. The collaboration combines Aptevo's multi…

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