NMRA
Neumora reports favorable NMRA-215 toxicology results
Neumora Therapeutics reported positive preclinical toxicology data for its NLRP3 inhibitor NMRA-215. The results support the advancement of the drug candidate to the clinic. The company plans to file its IND in late 2026.
NMRA
Neumora discontinues navacaprant after Phase 3 failures in depression
Neumora's Phase 3 KOASTAL-2 and -3 studies of navacaprant failed to meet primary endpoints for major depressive disorder, prompting the company to halt development. The company is implementing a 35% workforce reduction and refocusing on three pipeline programs with cash runway through Q3 2027.
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